Baker Mayfield, Bucky Irving and Rachaad White sparked a late game-winning drive to lift the Tampa Bay Buccaneers over Houston, sending TB to 2-0 and dropping the Texans to 0-2. Mayfield showed clutch poise while Irving and White fueled the offense in crunch time, hinting at a versatile backfield that'll be fantasy relevant in the weeks ahead.

In the other primetime-like matchup, the Chargers smothered Geno Smith in his home Raiders debut, snagging three interceptions and holding Las Vegas to nine points. The staunch defensive effort puts a spotlight on Chargers D/ST viability and raises questions about Seattle’s passing attack and Raiders’ week-to-week ceiling.

Falcons climb to second in the NFC South after a 22-6 Week 2 win at Minnesota, while the Buccaneers sit atop the division at 2-0. Panthers and Saints are both 0-2, with New Orleans getting a notable showing from Spencer Rattler (207 yards, 3 TDs, 0 INT) in a 26-21 defeat to San Francisco. Week 3 pits Atlanta against Carolina in Charlotte, a pivotal divisional test that could define early-season fantasy angles.

Jake Browning takes Cincinnati’s quarterback duties, flashing a stable fantasy floor around 20 points per game in his last starter stint, signaling weekly streaming viability in favorable matchups.

Denver’s WR pecking order shifts as Troy Franklin edges Marvin Mims Jr. for outside work, with Courtland Sutton anchoring the unit. Woody Marks is breaking out in Houston’s backfield, potentially becoming a top waiver RB and even a starter soon. PFF+ tools and in-season projections round out the plan for smart, early-week roster decisions.